Coccidioidomycosis

(San Joaquin fever, “Valley Fever”)

A coccidioidomycosis is a pulmonary or hematogenous spread disseminated disease, which is caused by the fungi posadasii Coccidioides immitis and C.. Mostly it is an acute, benign, asymptomatic or self-limited respiratory infection. The pathogen spreads occasionally and leads to focal infections in other tissues. If symptoms are present, there are symptoms of an infection of the lower respiratory tract or a nonspecific disseminated disease. The suspected diagnosis is based on clinical and epidemiological characteristics and confirmed by a chest x-ray, culture and serology. The therapy, if necessary, is usually with fluconazole, itraconazole, newer triazoles or amphotericin B.

(See also the “Coccidioidomycosis” the Infectious Diseases Society of America.)

A coccidioidomycosis is a pulmonary or hematogenous spread disseminated disease, which is caused by the fungi posadasii Coccidioides immitis and C.. Mostly it is an acute, benign, asymptomatic or self-limited respiratory infection. The pathogen spreads occasionally and leads to focal infections in other tissues. If symptoms are present, there are symptoms of an infection of the lower respiratory tract or a nonspecific disseminated disease. The suspected diagnosis is based on clinical and epidemiological characteristics and confirmed by a chest x-ray, culture and serology. The therapy, if necessary, is usually with fluconazole, itraconazole, newer triazoles or amphotericin B. (See also the “Coccidioidomycosis” the Infectious Diseases Society of America.) In North America, the endemic area for coccidioidomycosis includes the southwestern US Northern Mexico the affected areas close the southwestern United States, Arizona, the “Central Valley” of California, parts of New Mexico and Texas west of El Paso one. The area extends into northern Mexico and there are individual herd in parts of Central America and Argentina. About 30 to 60% of people living in endemic areas are eventually exposed to the fungus in their lives. In the US, about 150,000 infections develop per year; more than half of which is subclinical. Pathophysiology The infection is acquired by inhaling dust containing spores. Increase why certain professions (eg. as agriculture, construction) and the risk activities outdoors. Epidemics can occur when heavy rains that promote the growth of the mycelia, followed by drought and wind. With travelers infection can be evident even before outside endemic areas due to the delayed onset of clinical manifestations. After inhaling the spores of C. immitis convert into large, fabric-invasive Sphaerulae. The Sphaerulae enlarge and eventually rupture and set in each case thousands of endospores freely are the new Sphaerulae. Changes in the lungs are characterized by an acute, subacute or chronic granulomatous reaction with a fibrosis variable proportions. Lesions can lead to cavities or develop nodular, coin-shaped lesions. Occasionally, the disease progresses, developed with extensive pulmonary involvement, systemic dissemination, or both. It can form focal lesions in almost all tissues, mostly in the skin, subcutaneous tissue, bone (osteomyelitis) and the meninges (meningitis). A progressive coccidioidomycosis is uncommon in otherwise healthy people and is more common under the following circumstances: HIV infection using immunosuppressants Seniority second half of pregnancy or after birth Certain ethnic backgrounds (Filipino, African Americans, Native Americans, Latin Americans and Asians, in descending order of relative risk) symptoms and complaints Primary coccidioidomycosis most patients are asymptomatic; nonspecific respiratory symptoms, which also remind influenza, acute bronchitis or less from an acute pneumonia or pleural effusion, but happens occasionally. Of complaints come in descending order according to frequency u. a. fever, cough, chest pain, chills, Sputumbildung, sore throat and hemoptysis. Physical examination findings may be missing or be limited to isolated rales with or without damping on percussion over lung fields. Some patients develop hypersensitivity to the localized respiratory infection that is manifested by arthritis, conjunctivitis, erythema nodosum or erythema multiforme. Coccidioidomycosis Image courtesy of www.doctorfungus.com © 2005. var model = {thumbnailUrl: ‘/-/media/manual/professional/images/coccidioidomycosis_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/ – /media/manual/professional/images/coccidioidomycosis_high_de.jpg?la=de&thn=0 ‘, title:’ coccidioidomycosis ‘description:’ u003Ca id = “v38396399 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eEine hypersensitivity antigens u003ci u003eCoccidioides immitis u003c / i u003e may be as erythema nodosum

Health Life Media Team

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