Will Biogen’s Alzheimer’s Drug – Aduhelm Help with Dementia Treatment?

June 13, 2021

FDA endorsement of Biogen’s Alzheimer’s drug Aduhelm has triggered a major debate in dementia treatment.More than 6 million Americans are affected by Alzheimer’s or other dementias, the sixth-leading cause of death in the U.S.. By some professional estimates, the number of sufferers could, unfortunately, double in the decades ahead. Several high-profile FDA panel advisors quit after the controversial Biogen drug approval, which could generate billions of dollars in sales. Still,…

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What is ECF Volume Overload?

A volume overload refers generally to an expansion of the ECF volume. An expansion of the ECF volume typically occurs during heart failure, nephrotic syndrome and in liver cirrhosis. A renal sodium retention leads to an increase of total body sodium content. This increase results in varying degrees of volume overload. In heart failure, the decreased ECF volume leads to an increased effective circulating volume, which in turn causes the…

September 3, 2018
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What are Achilles Tendon Ruptures

September 3, 2018

Achilles (uh-KILL-eez) tendon rupture is an injury that impacts the back of your lower leg. It primarily happens in people playing sports. However, it can transpire in anyone. The Achilles tendon is a firm fibrous cord that links the muscles in the back of your calf to your heel bone. If you overstretch your Achilles tendon, it can tear (rupture) entirely or just partially. If your Achilles tendon ruptures, you…

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Wheezing And Asthma In Infants And Young Children

September 3, 2018

Wheezing is a relatively high-pitched whistling sound, which is generated by the movement of air through constricted or compressed small airways. It comes in the first years of life are common and is usually caused by a viral respiratory infection or asthma, but other possible causes include inhaled irritants or allergens, reflux, and heart failure. Recurrent episodes of wheezing are common in the early years; 1 of 3 children has…

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Wiskott-Aldrich Syndrome

The Wiskott-Aldrich syndrome is a combined B and T cell defect underlying is expressed in recurrent infections, eczema and thrombocytopenia. (See also Overview of immune deficiency disorders, and approach to the patient with an immunodeficiency disorder.) The Wiskott-Aldrich syndrome is a combined B and T cell defect underlying is expressed in recurrent infections, eczema and thrombocytopenia. (See also Overview of immune deficiency disorders, and approach to the patient with an…

September 3, 2018
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X-Linked Lymphoproliferative Syndrome Inherited

(Duncan’s syndrome) The X-linked lymphoproliferative syndrome is a result of a defect in the T-cells and natural killer cells and is characterized by an abnormal sensitivity to Epstein-Barr virus infections. This can lead to liver failure, immunodeficiency, lymphoma, fatal lymphoproliferative diseases or bone marrow aplasia. (See also Overview of immune deficiency disorders, and approach to the patient with an immunodeficiency disorder.) The X-linked lymphoproliferative syndrome is a result of a…

September 3, 2018
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X-Ray And Other Imaging Contrast Examinations

The main contraindication in X-ray contrast media studies is a suspicion of a perforation because free barium causes severe irritation to the mediastinum or peritoneum; water-soluble contrast agents are less irritating and can be used in cases of possible perforation. In elderly patients, storage and rotation for optimum positioning of barium and intraluminal air often causes difficulties. X-ray and other imaging contrast examinations are the entire GIT from the pharynx…

September 3, 2018
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X-Ray Contrast Media And Contrast Media Reactions

Iodinated contrast agents may be Radiopaque contrast agents are often used in radiography and fluoroscopy, to distinguish boundaries between tissues of similar X-ray density. Most contrast agents containing iodine. Iodinated contrast agents may be Ionic Nonionic Ionic contrast media, the salts are hyperosmolar as compared to blood. Ionic contrast agent should be used either for myelographic investigations, nor for injections in which it into the spinal canal (neurotoxic risk side…

September 3, 2018
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Zika Virus (Zv) Infections

The Zika virus is a flavivirus that is similar to viruses, dengue fever, yellow fever and West Nile fever. cause. A Zika virus infection is usually asymptomatic, but can cause fever, rash, joint pain, or conjunctivitis; a Zika virus infection during pregnancy can cause (a serious birth defects) and eye abnormalities microcephaly. The diagnosis is by enzyme-linked immunosorbent assay or a reverse transcriptase-PCR. posed. The treatment is symptomatic. Prevention includes…

September 3, 2018
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Von Willebrand Syndrome

(Von Willebrand’s disease) The von Willebrand syndrome is a genetic disease in which a lack of von Willebrand factor (vWF) is leading to a platelet dysfunction. Usually a slight bleeding is present. Screening tests show normal platelet counts and occasionally a slightly prolonged PTT. The diagnosis is made by the detection of low vWF antigen levels and an abnormal ristocetin cofactor activity. The treatment consists in a control of bleeding…

September 3, 2018
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