Liddle’S Syndrome

The Liddle’s syndrome is a rare hereditary disorder, with an increased activity of the epithelial sodium channel (ENaC), which causes the kidneys excrete potassium but retain too much sodium and water, leading to hypertension. The symptoms are hypertension, fluid retention, metabolic alkalosis. The diagnosis is made by measuring the urine electrolytes. Potassium-sparing diuretics are the best treatment. The Liddle syndrome is a rare autosomal dominant disorder of renal epithelial transport,…

September 3, 2018