Hereditary Nonpolyposis Colorectal Cancer

(Lynch syndrome) Hereditary nichtpolypöse colorectal cancer (HNPCC) is an autosomal dominant disease that is responsible for 3-5% of cases of colorectal cancer (CRC). The symptoms, initial diagnosis and treatment are similar to those of other forms of CRC. HNPCC is suspected on the basis of medical history and confirmed by genetic testing. Patients also require also controls in regard to the occurrence of other cancers, v. a. of endometrial and…

September 3, 2018