Fragile X-Associated Tremor Ataxia Syndrome (Fxtas)

Fragile X-associated tremor ataxia syndrome (FXTAS) is a genetic disease that usually affects men and tremor caused ataxia and dementia. Tremor is a common early symptom that is followed by ataxia, Parkinson’s disease and finally dementia. The diagnosis is confirmed by genetic testing. The tremor can often be alleviated with primidone, propranolol or anti-Parkinson’s drugs. FXTAS affects about 1/3000 men aged> 50 years. It results from a Premutation (50-200 CGG…

September 3, 2018