Fluoroquinolones

Fluoroquinolones are in two groups – based on antimicrobial spectrum and pharmacology – divided: Fluoroquinolones (see Table: fluoroquinolones) include a concentration-dependent bactericidal activity (efficacy) by inactivation of DNA gyrase and -Topoisomerase, of essential for bacterial DNA replication enzymes. Fluoroquinolones are in two groups – based on antimicrobial spectrum and pharmacology – divided: Older group: ciprofloxacin, norfloxacin, ofloxacin Newer Group: gemifloxacin, levofloxacin and moxifloxacin Many newer fluoroquinolones have been withdrawn due…

September 3, 2018
Read More >>