En The Respiratory

Urogenital and gastrointestinal tract; colostrum) where it provides an early antibacterial and antiviral defense. J-chains combine IgA with a dimer and together form secretory IgA. Secretory IgA is synthesized by plasma cells in the subepithelial regions of the gastrointestinal and respiratory tract. Selective IgA deficiency is relatively common but often has little clinical significance because there is a cross-functionality with other classes of antibodies. IgD is expressed together with IgM…

September 3, 2018
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