Disorders Of The Embden-Meyerhof Cycle

Disorders of the Embden-Meyerhof cycle are autosomal recessive diseases of erythrocyte metabolism that lead to hemolytic anemia. Pyruvate kinase deficiency is one such enzyme defect. In all these Stoffwechselwegdefekten hemolytic anemia occurs only in homozygotes. The exact mechanism of hemolysis is unknown. It found no spherocytes, but a small number of irregular spherically shaped red blood cells may be present. In general, the determination of ATP and diphosphoglycerate leads to…

September 3, 2018