Diagnostic Process Genetic

Gene probes are used to locate particular segments of normal or mutant DNA. Different types of probes can examine a wide range of sizes of the DNA sequence. A known DNA segment may be cloned and then fluorescently labeled (using fluorescence in situ hybridization [FISH]). This segment is then combined with the DNA sample. The labeled DNA binds to the complementary DNA segment and can be detected by measuring the…

September 3, 2018