Clindamycin is a lincosamide antibiotic (lincosamides, oxazolidinones and streptogramins), which is primarily bacteriostatic. It binds to the 50S subunit of the ribosome, thereby inhibiting protein synthesis. Pharmacology Clindamycin is well absorbed after oral administration and can be administered parenterally. Clindamycin diffuses well in all body fluids except cerebrospinal fluid and accumulates in phagocytes. Most of the substance is metabolized; the metabolites are excreted via the bile and urine. Indications The…

September 3, 2018