Central Diabetes Insipidus

(Vasopressin-Sensitive Diabetes insipidus) Diabetes insipidus (DI) is produced either by a vasopressin deficiency (synonym: antidiuretic hormone, ADH) as a result of hypothalamic-pituitary disorder (central DI [CDI]) or by renal vasopressin resistance (renal DI [NDI]). It comes to polyuria and polydipsia. The diagnosis is made by a thirst test that shows an inability to urine concentration; Vasopressin levels and response to vasopressin administration help to distinguish the CDI from NDI. The…

September 3, 2018