Carbapenems (imipenem, meropenem, doripenem and ertapenem) are bactericidal parenteral ?-lactam antibiotics which have an extremely broad spectrum of action. They are active against Haemophilus influenzae anaerobes Most Enterobacteriaceae (including those that produce ampC ?-lactamase and Extended-spectrum ?-lactamase [ESBL], although P. mirabilis tend to have higher imipenem minimum inhibition concentrations [MICs] have) methicillin-sensitive staphylococcus and streptococci, including S. pneumoniae (except possibly strains with reduced penicillin sensitivity). Most Enterococcus faecalis and many…

September 3, 2018