Carcinoma Of The Renal Pelvis And Ureters

Malignancies of the renal pelvis and ureters are mostly urothelial carcinoma (TTCs) or occasionally squamous cell carcinomas. Symptoms are hematuria and sometimes pain. Diagnosis is made by endoscopic biopsy using CT, cytology and at times. The therapy is surgery.

The TCC of the renal pelvis is responsible for approximately 7-15% of all kidney tumors. The TCC of the ureters accounts for about 4% of the tumors of the upper urinary tract. Risk factors are the same as those for bladder cancer (smoking, excessive phenacetin use, long-term use of cyclophosphamide, chronic irritation, exposure to certain chemicals). In addition, originating from the Balkans patients are predisposed to an endemic familial nephropathy inexplicably to develop a TCC of the upper urinary tract.

Malignancies of the renal pelvis and ureters are mostly urothelial carcinoma (TTCs) or occasionally squamous cell carcinomas. Symptoms are hematuria and sometimes pain. Diagnosis is made by endoscopic biopsy using CT, cytology and at times. The therapy is surgery. The TCC of the renal pelvis is responsible for approximately 7-15% of all kidney tumors. The TCC of the ureters accounts for about 4% of the tumors of the upper urinary tract. Risk factors are the same as those for bladder cancer (smoking, excessive phenacetin use, long-term use of cyclophosphamide, chronic irritation, exposure to certain chemicals). In addition, originating from the Balkans patients are predisposed to an endemic familial nephropathy inexplicably to develop a TCC of the upper urinary tract. Symptoms and discomfort for most patients is a hematuria the first symptom. If the bladder is affected, dysuria and urinary frequency may occur. An obstruction (obstructive uropathy) may be accompanied by colic. Rarely renal pelvic tumor causes hydronephrosis. Diagnostic sonography or CT with contrast cytology or histology in patients with unexplained Harnwegsymptomen is performed usually a sonography or CT with contrast. If the diagnosis can not be excluded, a cytological or histological analysis is performed to confirm. A ureteroscopy is performed when a biopsy of the upper urinary tract is required or urine cytology is positive, the source of malignant cells but is unclear. A CT scan of the abdomen and pelvis is performed to determine the extent of the tumor and a possible formation of metastases. Prognosis The prognosis depends on the depth of penetration into or through the uroepithelial wall that is difficult to determine. the curative rate is> 90% for patients with localized, superficial tumor, for patients with a deeply invasive tumor but only 10-15%. A cure is unlikely if the tumor penetrates the wall or distant metastases occur. Excision or ablation therapy monitoring after treatment with cystoscopy The usual therapy is a radical nephroureterectomy with excision of a bubble cuff. In some carefully selected patients a partial Ureterektomie may be indicated (eg., Patients with a distal Uretertumor, renal failure or a solitary kidney). Sometimes a laser fulguration for exactly classified and appropriately displayable renal pelvic tumors or low-malignant Uretertumoren is possible. Occasionally a drug such as mitomycin C or BCG is instilled. However, the effectiveness of a laser or chemotherapy has not yet been proven. At regular intervals, a cystoscopy is indicated, as malignancies of the renal pelvis and ureter tend to recur in the bladder, and such a relapse if it is detected early, it can be treated by fulguration, transurethral resection or intravesical instillations. Metastases, the procedure corresponds to the metastatic bladder cancer. Key points risk of renal pelvis and ureter cancer increases with smoking, phenacetin or Cyclophosphamidgebrauch, chronic irritation or exposure to certain chemicals. Perform sonography or CT with contrast medium through when Harntraktsymptome are inexplicable. Confirm the diagnosis by polysomnography. You excise tumors or perform an ablation, usually using radical nephroureterectomy and monitor the patient with periodic cystoscopy.

Health Life Media Team

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