Bullous Keratopathy

When bullous keratopathy (bullae) are present in the corneal epithelium bubbles, due to a disease of the corneal endothelium.

The bullous keratopathy caused by corneal edema, which develops when the endothelium can no longer maintain the dehydrated normal state of the cornea. Most frequently Fuchs dystrophy or endothelial corneal trauma is the cause. The Fuchs dystrophy is a genetic disorder that results in the age of 50-60 years for a bilateral progressive endothelial cell loss and sometimes symptomatic bullous keratopathy. The Fuchs dystrophy may be autosomal dominant with incomplete penetrance. Another common cause of bullous keratopathy is an endothelial corneal trauma during intraocular surgery (z. B. cataract removal) or can occur after the implantation of an unfavorably shaped or poorly placed artificial lens. The bullous keratopathy after cataract removal is pseudophakic (if an intraocular lens is implanted) aphakic (if no intraocular lens is implanted) or called bullous keratopathy.

When bullous keratopathy (bullae) are present in the corneal epithelium bubbles, due to a disease of the corneal endothelium. The bullous keratopathy caused by corneal edema, which develops when the endothelium can no longer maintain the dehydrated normal state of the cornea. Most frequently Fuchs dystrophy or endothelial corneal trauma is the cause. The Fuchs dystrophy is a genetic disorder that results in the age of 50-60 years for a bilateral progressive endothelial cell loss and sometimes symptomatic bullous keratopathy. The Fuchs dystrophy may be autosomal dominant with incomplete penetrance. Another common cause of bullous keratopathy is an endothelial corneal trauma during intraocular surgery (z. B. cataract removal) or can occur after the implantation of an unfavorably shaped or poorly placed artificial lens. The bullous keratopathy after cataract removal is pseudophakic (if an intraocular lens is implanted) aphakic (if no intraocular lens is implanted) or called bullous keratopathy. Bullous keratopathy Image courtesy of Prof. J. Wollensak via the Online Journal of Ophthalmology (www.onjoph.com). var model = {thumbnailUrl: ‘/-/media/manual/professional/images/bullous_keratopathy_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/-/media/manual/professional/images/bullous_keratopathy_high_de.jpg?la = en & thn = 0 ‘, title:’ Bullous keratopathy ‘description:’ u003Ca id = “v37894218 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eDurch disease or trauma to the corneal endothelium may lead to the formation of bullae that burst and a corneal erosion (as well as secondary to infection and ulceration) may result. u003c / p u003e u003c / div u003e ‘ credits: ‘image courtesy of Prof. J. Wollensak via the online Journal of Ophthalmology (www.onjoph.com).’

Health Life Media Team

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