Brain Tumors In Children At A Glance

Brain tumors are the most common solid cancer in children <15 years and the second leading cause of cancer death. Diagnosis is generally by imaging methods (usually magnetic therapy) and biopsy. Treatment consists of surgical resection, chemotherapy and radiation.

The cause of most CNS tumors of childhood is unknown, but two well-established risk factors, ionizing radiation (eg. As high-dose irradiation of the skull) and specific genetic syndromes (z. B. neurofibromatosis).

Brain tumors are the most common solid cancer in children <15 years and the second leading cause of cancer death. Diagnosis is generally by imaging methods (usually magnetic therapy) and biopsy. Treatment consists of surgical resection, chemotherapy and radiation. The cause of most CNS tumors of childhood is unknown, but two well-established risk factors, ionizing radiation (eg. As high-dose irradiation of the skull) and specific genetic syndromes (z. B. neurofibromatosis). The most common CNS tumors in children are ependymomas (in order) astrocytomas medulloblastomas symptoms and complaints Increased intracranial pressure is the cause of the most common manifestations that comprise headache nausea and vomiting irritability lethargy solve behavioral changes in gait and balance disorders diagnostic MRI biopsy MRI is the test of choice because it provides more detailed images of parenchymal tumors and can detect tumors in the posterior fossa, in the subarachnoid space and the arachnoid and pia mater. CT may be performed, but is less sensitive and less specific. A biopsy can be performed to confirm the diagnosis and determine the type of tumor and degree. Once the diagnosis is made, staging, Klssifizierung and risk assessment are determined. The staging includes an MRI of the entire spine, lumbar puncture for CSF cytology and postoperative MRI to evaluate any residual tumor. The WHO has created a widely used rating system. The risk assessment is based on age, degree of residual tumor and the detection of the spread of disease. Therapy Surgical resection radiotherapy, chemotherapy or a combination thereof After removal of the tumor are usually radiotherapy, chemotherapy or both in connection required. Participation in a clinical trial should be considered for all children with a brain tumor considered. Optimal treatment requires a multidisciplinary team of pediatric oncologists, pediatric neuro-oncologists, pediatric neurosurgeons, pathologists, radiologists and neuro radiation oncologists who are experienced in the treatment of brain tumors in children. Because radiation therapy for brain tumors is technically demanding, the children should be transferred if possible to centers that have experience in this area. Further information WHO evaluation of tumors of the central nervous system

Health Life Media Team

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