Behcet’S Disease

(Behcet’s disease)

The Behcet’s disease is a multisystemic, recurrent, chronic vasculitis with mucositis. Common manifestations include recurrent oral ulcers, ocular inflammation, genital ulcers and skin lesions. The most severe manifestations are blindness, neurological or gastrointestinal manifestations, venous thrombosis and arterial aneurysms. The diagnosis is made clinically according to international criteria. Treatment is usually symptomatic, but may require the use of corticosteroids with or without immunosuppressive drugs for more severe manifestations.

The Behcet’s disease is an inflammatory disorder that may include a Vaskulitisder small and large arteries and / or veins. Arterial and venous thrombosis can also occur.

The Behcet’s disease is a multisystemic, recurrent, chronic vasculitis with mucositis. Common manifestations include recurrent oral ulcers, ocular inflammation, genital ulcers and skin lesions. The most severe manifestations are blindness, neurological or gastrointestinal manifestations, venous thrombosis and arterial aneurysms. The diagnosis is made clinically according to international criteria. Treatment is usually symptomatic, but may require the use of corticosteroids with or without immunosuppressive drugs for more severe manifestations. The Behcet’s disease is an inflammatory disorder that may include a Vaskulitisder small and large arteries and / or veins. Arterial and venous thrombosis can also occur. The disease occurs almost equally common in men and women, shows severe cases likely in men and usually begins in the third decade of life. Occasionally, the disease develops in children. The incidence varies depending on the location. The Behcet’s disease is very common along the Silk Road from the Mediterranean to China; it is unusual in the US. The cause is unknown. There are immunological (incl. Autoimmune) and viral or bacterial trigger suspects and HLA-B51 is the main risk factor. The prevalence of HLA-B51 allele is> 15% among people from Europe, the Middle East and the Far East, but is niederig or not missing among people from Africa, Oceania and South America. Neutrophil infiltration is found in Bioptaten of oral aphthous ulcers; pathognomonic are erythema nodosum and pathergische lesions, but not histological changes. Symptoms and complaints mucocutaneous symptoms Almost all patients have recurrent painful oral ulcers similar to those of aphthous stomatitis and usually represent the first disease manifestation. The ulcers are round or oval, 2-10 mm in diameter and shallow or deep with a central yellowish necrotic center, they can occur anywhere in the oral cavity, often in clusters. The ulcers persist 1-2 weeks. Similar ulcers occur on the penis and scrotum, on the vulva, where they cause pain, or in the vagina, where they are little or not painful. Behcet’s disease (oral aphthous ulcers) Image courtesy of O. H. Gottfried Naumann about the Online Journal of Ophthalmology (www.onjoph.com). var model = {thumbnailUrl: ‘/-/media/manual/professional/images/behcets_syndrome_oral_aphthae_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/-/media/manual/professional/images/behcets_syndrome_oral_aphthae_high_de.jpg?la = de & thn = 0 ‘, title:’ Behcet’s disease (oral aphthous ulcers) “, description: ‘ u003Ca id = ” v37892934 “”class = “” anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eZu systemic findings in Behcet’s disease can include mouth ulcers in the mouth u003c / p u003e u003c / div u003e ‘credits’. image courtesy of Gottfried OH Naumann about the Online Journal of Ophthalmology (www.onjoph.com) ‘hideCredits: false

Health Life Media Team

Leave a Reply