Anorectal Cancers

When anorectal cancer each year about 7000 cases and> 900 cases fatal counting.

The most common anorectal cancer is adenocarcinoma. Squamous (nichtverhornende Plattenepithelzell- or basaloid carcinoma) of the anorectal region are responsible for 3-5% of colon carcinomas. Rare the basal cell carcinoma, Bowen’s disease are (intradermal carcinoma), extramammary Paget’s disease, kloakogenes carcinoma and malignant melanoma. Other tumors are lymphomas and various sarcomas. Metastasis occurs along the Lymphabflusswegen the rectum and in the inguinal lymph nodes.

When anorectal cancer each year about 7000 cases and> 900 cases fatal counting. The most common anorectal cancer is adenocarcinoma. Squamous (nichtverhornende Plattenepithelzell- or basaloid carcinoma) of the anorectal region are responsible for 3-5% of colon carcinomas. Rare the basal cell carcinoma, Bowen’s disease are (intradermal carcinoma), extramammary Paget’s disease, kloakogenes carcinoma and malignant melanoma. Other tumors are lymphomas and various sarcomas. Metastasis occurs along the Lymphabflusswegen the rectum and in the inguinal lymph nodes. Risk factors include infection with human papilloma virus (HPV), chronic fistulae, preirradiated anal skin, leukoplakia, lymphogranuloma venereum, and condylomata acuminata. People who practice receptive anal sex, are at particularly high risk. Patients with HPV infection can manifest dysplasia in only small bold or normal-appearing Analepithelium have (anal intraepithelial neoplasia – histologically categorized in grade I, II or III). These changes are more common in HIV-infected patients. Higher Dysplasiegrade may progress to invasive carcinoma. It is unclear whether early diagnosis and eradication affects the long-term results, so there is no clear screening recommendations. Bleeding during bowel movements is the most common first symptom. Some patients have pain, tenesmus or a feeling of incomplete evacuation. A mass may be palpable during digital Rektumuntersuchung. Whenever a rectal haemorrhage occurs, also vorliegendes carcinoma must be excluded, even in patients with obvious hemorrhoids or diverticulosis. Typically, a colonoscopy is performed, however, a change made by a dermatologist or surgeon skin biopsy of lesions in the vicinity of the gastric mucosa limit (Z-line) may be needed. For staging are CT, MRI or PET advisable. An extended local excision is often a satisfactory treatment of perianal cancer. A combined radiochemotherapy results in anal squamous and kloakogenen tumors in higher cure rates. An abdominoperineal resection is appropriate when radiation and chemotherapy do not lead to complete tumor remission and there are no metastases outside the radiation field.

Health Life Media Team

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