Acute Febrile Neutrophilic Dermatosis

(Sweet’s syndrome)

The acute febrile neutrophilic dermatosis goes with druckdolenten, indurated, dark red papules and plaques with significant edema in the upper dermis accompanied, as well as a dense Neutrophileninfiltrat. The cause is unknown. It often occurs in the underlying Kreb, v. a. in hematological cancer.

The acute febrile neutrophilic dermatosis goes with druckdolenten, indurated, dark red papules and plaques with significant edema in the upper dermis accompanied, as well as a dense Neutrophileninfiltrat. The cause is unknown. It often occurs in the underlying Kreb, v. a. in hematological cancer. Etiology acute febrile neutrophilic dermatosis may occur with different disorders. It is often divided into three categories: classic, malignancy-associated and drug-induced. Disorders and drugs associated with acute febrile neutrophilic dermatosis classification disorder / drug Classic Acute respiratory diseases GI infection Inflammatory and autoimmune diseases pregnancy malignancy-associated Acute myeloid leukemia myelodysplastic syndrome drug induced granulocyte colony-stimulating factor (G-CSF, the most common medical cause) antibiotics antiepileptic drugs on particular (z. As abacavir, furosemide, hydralazine, NSAIDs, oral contraceptives, retinoids) About 25% of patients have an underlying cancer, of which 75% hematologic cancers, especially myelodysplastic syndromes and acute myeloid leukemia. The classic acute febrile neutrophilic dermatosis predominantly affects women aged 30-50 years with a ratio of women to men by 3: 1. In contrast, men who fall ill, mostly in older age (60-90 years). The cause is unknown. However, type 1 helper T cell cytokines, including IL-2 and interferon-?, spreading and could play a role in the formation of lesions. Symptoms and signs Patients have fever with increased Neutrophilzahl and sensitive, dark red plaques or papules, usually on the face, neck and upper extremities, especially on the back of the hand. Oral lesions may also occur. Rarely are bullous and pustular lesions before. The changes often occur in spurts and may appear annular. Each attack is preceded by fever and hold them for several days. The acute febrile neutrophilic dermatosis which results from a hematological cancer can cause a subcutaneous form, which typically has 2-3 cm erythematous nodules and usually affects the extremities. When it occurs on the lower extremities, this form of erythema nodosum may be similar. Acute febrile neutrophilic dermatosis (Sweet’s syndrome) © Springer Science + Business Media var model = {thumbnailUrl: ‘/-/media/manual/professional/images/426-sweets-syndrome-slide-3-springer-high_de.jpg?la = en & thn = 0 & mw = 350 ‘, imageUrl:’ /-/media/manual/professional/images/426-sweets-syndrome-slide-3-springer-high_de.jpg?la=de&thn=0 ‘, title:’ acute febrile neutrophilic dermatosis (Sweet’s syndrome), ‘description’ u003Ca id = “v37894795 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eDiese figure shows classic erythematous plaques with vesicular limits on the neck and face with a woman with acute febrile neutrophilic dermatosis (Sweet’s syndrome). The lesions consist of painful reddened to purple nodules that may grow together to form plaques and are distributed asymmetrically on the upper extremities

Health Life Media Team

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