Acne Vulgaris

(Acne)

Acne vulgaris (acne) is accompanied by the formation of comedones (blackheads), papules, pustules, nodules and / or cysts due to obstruction and inflammation of the hair follicle sebaceous unit. Acne develops on the face and upper body. Most young people are affected. The diagnosis is made clinically. Treatment depends on the severity and performed with many topical and systemic drugs that target the reduction of sebum, the Komedonenproduktion, the inflammatory response and the number of bacteria and normalize keratinization.

Acne is the most common skin disorder in the US, affecting 80% of the population at some point in their lives.

Acne vulgaris (acne) is accompanied by the formation of comedones (blackheads), papules, pustules, nodules and / or cysts due to obstruction and inflammation of the hair follicle sebaceous unit. Acne develops on the face and upper body. Most young people are affected. The diagnosis is made clinically. Treatment depends on the severity and performed with many topical and systemic drugs that target the reduction of sebum, the Komedonenproduktion, the inflammatory response and the number of bacteria and normalize keratinization. Acne is the most common skin disorder in the US, affecting 80% of the population at some point in their lives. Pathophysiology Acne occurs by the interaction of four main factors: Excessive sebum follicular plugging with sebum and keratinocytes colonization of the follicle by Propionibacterium acnes (a normal human anaerobes) release of several inflammatory mediators acne can be classified as non-flammable: characterized by comedones Flammable by papules, pustules, in nodules and cysts. Non-inflammatory acne comedones are tallowy plugs which are affected in the follicles. A distinction is made open and closed comedones, depending on whether the follicle is dilated to the skin surface or closed. The plugs are easy to put on open comedones, are difficult to remove from closed comedones. Closed comedones are the Vorläuferläsion of inflammatory acne. Inflammatory acne papules and pustules occur when P. acnes closed comedones colonized, which breaks up the sebum into free fatty acids that irritate the follicular epithelium and trigger an inflammatory response by neutrophils and lymphocytes later, which further disrupts the epithelium. The inflamed follicle ruptiert into the dermis (sometimes by physically manipulating or strong rubbing triggered), where the contents of the comedones cause further local Entzündungssreaktion, leading to the formation of papules. If the inflammation is intense, grossly purulent pustules occur. Inflammatory acne with hyperpigmentation © Springer Science + Business Media var model = {thumbnailUrl: ‘/-/media/manual/professional/images/279_acne_slide_18_springer_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/ – / media / manual /professional/images/279_acne_slide_18_springer_high_de.jpg?la=de&thn=0 ‘, title:’ Inflammatory acne with hyperpigmentation ‘description:’ ‘credits’ © Springer Science + Business Media’, hideCredits: false, hideTitle: false, hideFigure : false, hideDescription: true}; var panel = $ (MManual.utils.getCurrentScript ()) Closest ( ‘image-element-panel.’). ko.applyBindings (model, panel.get (0)); Nodules and cysts are other manifestations of inflammatory acne. Nodes are deeper lesions, which may include> 1 follicles and cysts are large fluctuations in knots. Etiology The most common trigger is puberty During puberty stimulates increased androgen production sebum production and hyperproliferation of keratinocytes. Other triggers include hormonal changes that occur with pregnancy or the menstrual cycle Occlusive cosmetics, detergents, lotions and clothing High humidity and sweating A correlation between the exacerbation of acne and certain foods, inadequate facial hygiene, masturbation or sex is unfounded. Some studies suggest a possible association with dairy products and foods with a high glycemic index. Due to the anti-inflammatory effect of sunlight acne can go back in the summer months. Suggested links between acne and hyperinsulinism must be clarified further. Some drugs and chemicals (eg. Corticosteroids, lithium, phenytoin, isoniazid) aggravate acne or cause acneiform eruptions. Symptoms and complaints skin lesions and scarring can be a significant emotional burden. Nodules and cysts can be painful. Often lesions of different stages are side by side. Acne with large comedones © Springer Science + Business Media var model = {thumbnailUrl: ‘/-/media/manual/professional/images/281_acne_slide_21_springer_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/ – / media / manual /professional/images/281_acne_slide_21_springer_high_de.jpg?la=de&thn=0 ‘, title:’ acne with large comedones’ description: ” credits’ © Springer Science + Business Media ‘, hideCredits: false, hideTitle: false, hideFigure : false, hideDescription: true}; var panel = $ (MManual.utils.getCurrentScript ()) Closest ( ‘image-element-panel.’). ko.applyBindings (model, panel.get (0)); Acne with comedones pinna © Springer Science + Business Media var model = {thumbnailUrl: ‘/-/media/manual/professional/images/282_acne_slide_24_springer_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/ – / media / ? manual / professional / images / 282_acne_slide_24_springer_high_de.jpg lang = en & thn = 0 ‘, title:’ acne with ear cup comedones’ description: ” credits’ © Springer Science + Business Media ‘, hideCredits: false, hideTitle: false , hideFigure: false, hideDescription: true}; var panel = $ (MManual.utils.getCurrentScript ()) Closest ( ‘image-element-panel.’). ko.applyBindings (model, panel.get (0)); Comedones occur as “whiteheads” or “blackheads”. Whiteheads (closed comedones) are flesh-colored or whitish lesions of 1-3 mm diameter. Blackheads (open comedones) look similar, but have a black center. Skin lesion (pimple) Figure provided by Thomas Habif, M.D. var model = {thumbnailUrl: ‘/-/media/manual/professional/images/skin_lesion_pustule_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/-/media/manual/professional/images/skin_lesion_pustule_high_de.jpg?la = en & thn = 0 ‘, title:’ skin lesion (pimple) ‘description:’ u003Ca id = “v37894423 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003ePusteln are raised

Health Life Media Team

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