Tay-Sachs Disease And Sandhoff Disease

The Tay-Sachs disease and Sandhoff disease are Sphingolipidoses, an inherited metabolic disorder caused by a Hexosaminidasemangel leading to severe neurological symptoms and early death. Gangliosides are complex sphingolipids in the brain. The two forms, GM1 and GM2, both go with a lysosomal storage disease associated. One distinguishes two main types of GM2 Gangliosidosis, both of which can be caused by many different mutations. The Tay-Sachs disease and Sandhoff disease are…

September 3, 2018
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