Thin Basement Membrane

(Benign familial hematuria) Under the syndrome of thin basement membrane ( “thin basement membrane disease”) is defined as a diffuse thinning in healthy people 300-400 nm thick glomerular basement membrane at about 150-225 nm. The thin basement membrane is a kind of nephritic syndrome. It is hereditary and is usually transmitted as an autosomal dominant. Not all genetic mutations have been characterized so far. In some affected families but mutations…

September 3, 2018
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Minimal-Change Glomerulonephritis

(Lipoid nephrosis; “nil disease”) The minimal change disease causes – mostly in children – the abrupt onset of edema and severe proteinuria. Typically, the kidney function remains normal. Diagnosis is based on clinical criteria or kidney biopsy. The prognosis is excellent. The therapy consists of the administration of corticosteroids or non-responders with the administration of cyclophosphamide or cyclosporin. The minimal change disease (MCGN) is the most common cause of nephrotic…

September 3, 2018
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Membranous Nephropathy

(Membranous glomerulonephritis) As membranous glomerulonephritis (MGN) is defined as the deposition of immune complexes in the glomerular basement membrane (GBM) thickening under the same. The cause is generally unknown, although there are secondary forms, which are due to medications, infections, autoimmune disorders and cancer diseases. One of the manifestations has a gradual onset with edema and severe proteinuria with normal urine sediment, normal renal function and normal to elevated blood…

September 3, 2018
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Immunoglobulin A Nephropathy

(IgA nephropathy, Berger’s disease) IgA nephropathy (IgAN) is a deposition of IgA immune complexes in the glomeruli. It manifests itself as a slowly progressive hematuria, proteinuria and renal failure often. The diagnosis is based on the findings of urine and renal biopsy. The prognosis is generally good. As treatment options are ACE inhibitors, angiotensin II receptor antagonists, corticosteroids, immunosuppressants and polyunsaturated omega-3 fatty acid into consideration. IgA nephropathy (IgAN) is…

September 3, 2018
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Hereditary Nephritis

(Alport syndrome) is a hereditary nephritis is a genetically heterogeneous disorder characterized by a nephritic syndrome characterized, often with hearing loss and (d h hematuria, proteinuria, hypertension, renal failure possible..) – rarely – ophthalmological symptoms. The cause is a genetic mutation, the type IV collagen in question. Diagnosis is made by medical history, including family history, urinalysis, and biopsy (kidney or skin). The treatment is the same as that in…

September 3, 2018
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